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Journal article

Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis.

Abstract:

OBJECTIVES: Extracellular inorganic pyrophosphate (ePPi) inhibits certain forms of pathological mineralization while promoting others. Three molecules involved in ePPi regulation are important candidates for the development of calcium pyrophosphate dihydrate chondrocalcinosis (CPPD CC). These include ANKH, ectonucleotide pyrophosphatase (ENPP1) and TNAP. We have previously showed that genetic variation in ANKH is a cause of autosomal dominant familial CC and also some sporadic cases of CPPD C...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/kel338

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More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Rheumatology (Oxford, England)
Volume:
46
Issue:
4
Pages:
586-589
Publication date:
2007-04-01
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Source identifiers:
108314
Language:
English
Keywords:
Pubs id:
pubs:108314
UUID:
uuid:11067d43-41f2-472b-8094-1b4608f1d144
Local pid:
pubs:108314
Deposit date:
2012-12-19

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