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In situ macromolecular crystallography using microbeams.

Abstract:

Despite significant progress in high-throughput methods in macromolecular crystallography, the production of diffraction-quality crystals remains a major bottleneck. By recording diffraction in situ from crystals in their crystallization plates at room temperature, a number of problems associated with crystal handling and cryoprotection can be side-stepped. Using a dedicated goniometer installed on the microfocus macromolecular crystallography beamline I24 at Diamond Light Source, crystals ha...

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Publication status:
Published

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Publisher copy:
10.1107/s0907444912006749

Authors


Aishima, J More by this author
Morgan, AW More by this author
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Journal:
Acta crystallographica. Section D, Biological crystallography
Volume:
68
Issue:
Pt 5
Pages:
592-600
Publication date:
2012-05-05
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
URN:
uuid:10e11434-47af-4c9b-adb2-feb8c7a458b1
Source identifiers:
325543
Local pid:
pubs:325543

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