- Abstract:
-
KaiA is a two-domain circadian clock protein in cyanobacteria, acting as the positive element in a feedback loop that sustains the oscillation. The structure of the N-terminal domain of KaiA is that of a pseudo-receiver, similar to those of bacterial response regulators, which likely interacts with components of the clock-resetting pathway. The C-terminal domain of KaiA is highly conserved among cyanobacteria and enhances the autokinase activity of KaiC. Here we present the NMR structure of t...
Expand abstract - Publisher copy:
- 10.1073/pnas.0305516101
-
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- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 101
- Issue:
- 6
- Pages:
- 1479-1484
- Publication date:
- 2004-02-05
- DOI:
- EISSN:
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1091-6490
- ISSN:
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0027-8424
- URN:
-
uuid:10d72c57-750a-4d16-a12c-1b260eaf1281
- Source identifiers:
-
196791
- Local pid:
- pubs:196791
- Copyright date:
- 2004
Journal article
NMR structure of the KaiC-interacting C-terminal domain of KaiA, a circadian clock protein: implications for KaiA-KaiC interaction.
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