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Measuring the blockade of malaria transmission - An analysis of the Standard Membrane Feeding Assay

Abstract:

The standard membrane feeding assay (SMFA) is currently considered to be the 'gold standard' for assessing the effectiveness of malaria transmission blocking interventions (TBIs) in vivo. The operation and analysis of SMFAs has varied between laboratories: field scientists often measure TBI efficacy as a reduction in the prevalence of infected mosquitoes whilst laboratory scientists are more likely to quote efficacy as a change in the number of oocysts within the mosquito. These metrics give ...

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Authors


Churcher, TS More by this author
Blagborough, AM More by this author
Ramakrishnan, C More by this author
Kapulu, MC More by this author
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Journal:
International Journal for Parasitology
Volume:
42
Issue:
11
Pages:
1037-1044
Publication date:
2012-10-05
DOI:
EISSN:
1879-0135
ISSN:
0020-7519
URN:
uuid:10bf2fc8-d7af-4ea0-b611-6ad9d4491a89
Source identifiers:
359846
Local pid:
pubs:359846

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