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Genetic developments in autoimmune thyroid disease: an evolutionary process.

Abstract:

The identification of genes placing individuals at an increased risk for the development of autoimmune thyroid disease (AITD) has been a slow process. However, over the last 20 years or so real progress has been made with the mapping of novel loci, via a number of different approaches. First, through the use of traditional immunological methods, Human Leucocyte Antigen (HLA)/Major Histocompatibility Complex (MHC) was the first gene region to be associated with AITD and consistent replications...

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Authors


Zeitlin, AA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Journal:
Clinical endocrinology
Volume:
68
Issue:
5
Pages:
671-682
Publication date:
2008-05-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:10a66e8d-db70-4625-9e3d-dc866c800943
Source identifiers:
176374
Local pid:
pubs:176374

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