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Use of intravenous etomidate to control acute psychosis induced by the hypercortisolaemia in severe paediatric Cushing's disease.

Abstract:

BACKGROUND: Psychosis secondary to paediatric Cushing's disease (CD) is extremely rare and presents a significant management challenge. METHOD: We report a 14.7-year-old CD patient with acute psychosis and self-inflicted injuries following failed transsphenoidal pituitary surgery. Her mental state rapidly deteriorated precluding medical therapy. RESULTS: Emergency intravenous low-dose etomidate infusion (3-3.5 mg/h) with dose titration according to the serum cortisol combined with a hydrocor...

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Publication status:
Published

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Publisher copy:
10.1159/000324419

Authors


Westphal, B More by this author
Allgrove, J More by this author
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Journal:
Hormone research in paediatrics
Volume:
75
Issue:
6
Pages:
441-446
Publication date:
2011
DOI:
EISSN:
1663-2826
ISSN:
1663-2818
URN:
uuid:10a5e860-806e-4bd8-99bc-d9777271cf44
Source identifiers:
138382
Local pid:
pubs:138382

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