Antibiotic resistance and enhanced insecticide catabolism as consequences of steroid induction in the gram-negative bacterium Comamonas testosteroni.

Journal article

The effects of steroid induction on antibiotic resistance against the fungal steroid fusidic acid (ramycin; 16-(acetyloxy)-3 alpha,11 alpha-dihydroxy-29-dammara-17(20), 24-dien-21-oic-acid) as well as on carbonyl reduction and degradation of the novel anti-insect agent NKI 42255 (2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone) were studied in the Gram-negative soil bacterium Comamonas testosteroni strain ATCC 11996. Cells grown with testosterone as inducing agent showed a 5-6-fold ...

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Authors: Oppermann, U; Belai, I; Maser, E

• Journal: Journal of steroid biochemistry and molecular biology
• Volume: 58
• Issue: 2
• Pages: 217-223
• Publication date: 1996-05-01
• DOI: 10.1016/0960-0760(96)00021-0
• EISSN: 1879-1220
• ISSN: 0960-0760
• Language: English
• Keywords: Anti-Bacterial Agents; Testosterone; Gram-Negative Aerobic Bacteria; Fusidic Acid; Drug Resistance, Microbial; Metyrapone; Insecticides; Steroids