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Artificial and engineered chromosomes: developments and prospects for gene therapy.

Abstract:

At the gene therapy session of the ICCXV Chromosome Conference (2004), recent advances in the construction of engineered chromosomes and de novo human artificial chromosomes were presented. The long-term aims of these studies are to develop vectors as tools for studying genome and chromosome function and for delivering genes into cells for therapeutic applications. There are two primary advantages of chromosome-based vector systems over most conventional vectors for gene delivery. First, the ...

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Publication status:
Published

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Publisher copy:
10.1007/s00412-005-0017-5

Authors


Journal:
Chromosoma
Volume:
114
Issue:
4
Pages:
230-241
Publication date:
2005-09-01
DOI:
EISSN:
1432-0886
ISSN:
0009-5915
Source identifiers:
53485
Language:
English
Keywords:
Pubs id:
pubs:53485
UUID:
uuid:10884b0c-454e-4cbf-8b27-f198648cd604
Local pid:
pubs:53485
Deposit date:
2012-12-19

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