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Journal article

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss.

Abstract:

OBJECTIVE: Overweight and obesity are associated with a dyslipidaemia which can be improved by weight loss. Whether genetic predisposition to an adverse lipid profile modifies such beneficial effects of weight loss on lipid levels in overweight and obese individuals was examined. DESIGN AND METHODS: White European participants (n = 374) who completed a 12-month weight loss trial were genotyped for 36 lipid-associated single nucleotide polymorphisms (SNPs), previously identified in genome-wide...

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Publication status:
Published

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Publisher copy:
10.1002/oby.20328

Authors


Walker, CG More by this author
Holzapfel, C More by this author
Mander, AP More by this author
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Journal:
Obesity (Silver Spring, Md.)
Volume:
21
Issue:
12
Pages:
2589-2595
Publication date:
2013-12-05
DOI:
EISSN:
1930-739X
ISSN:
1930-7381
URN:
uuid:106b08b3-93de-4400-bbf6-102e6a883161
Source identifiers:
417944
Local pid:
pubs:417944

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