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FGF4 independent derivation of trophoblast stem cells from the common vole.

Abstract:

The derivation of stable multipotent trophoblast stem (TS) cell lines from preimplantation, and early postimplantation mouse embryos has been reported previously. FGF4, and its receptor FGFR2, have been identified as embryonic signaling factors responsible for the maintenance of the undifferentiated state of multipotent TS cells. Here we report the derivation of stable TS-like cell lines from the vole M. rossiaemeridionalis, in the absence of FGF4 and heparin. Vole TS-like cells are similar t...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0007161

Authors


Grigor'eva, EV More by this author
Shevchenko, AI More by this author
Mazurok, NA More by this author
Elisaphenko, EA More by this author
Zhelezova, AI More by this author
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Program of the Russian Academy of Sciences More from this funder
Integration Interdisciplinary Project of the Siberian Branch of the Russian Academy of Sciences More from this funder
Russian Foundation for Basic Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS One Journal website
Volume:
4
Issue:
9
Pages:
Article: e7161
Publication date:
2009
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:106544c7-cf88-4939-8824-1e48c28e57ae
Source identifiers:
100278
Local pid:
pubs:100278

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