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Journal article

The type III needle and the damage done.

Abstract:

Many Gram-negative pathogens translocate virulence proteins directly into host cells using a type III secretion system. This complex secretion machinery is composed of approximately 25 different proteins that assemble to span both bacterial membranes, and contact the host cell to form a direct channel between the bacterial and host cell cytoplasms. Assembly of the system and efficient secretion of virulence proteins through this apparatus require specific chaperones. Although the machinery is...

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Publication status:
Published

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Publisher copy:
10.1016/j.sbi.2005.10.007

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Current opinion in structural biology
Volume:
15
Issue:
6
Pages:
700-707
Publication date:
2005-12-05
DOI:
EISSN:
1879-033X
ISSN:
0959-440X
URN:
uuid:106038a9-6d5c-4f1a-b16d-32f371079997
Source identifiers:
24907
Local pid:
pubs:24907

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