- Abstract:
-
Many Gram-negative pathogens translocate virulence proteins directly into host cells using a type III secretion system. This complex secretion machinery is composed of approximately 25 different proteins that assemble to span both bacterial membranes, and contact the host cell to form a direct channel between the bacterial and host cell cytoplasms. Assembly of the system and efficient secretion of virulence proteins through this apparatus require specific chaperones. Although the machinery is...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.sbi.2005.10.007
-
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- Journal:
- Current opinion in structural biology
- Volume:
- 15
- Issue:
- 6
- Pages:
- 700-707
- Publication date:
- 2005-12-05
- DOI:
- EISSN:
-
1879-033X
- ISSN:
-
0959-440X
- URN:
-
uuid:106038a9-6d5c-4f1a-b16d-32f371079997
- Source identifiers:
-
24907
- Local pid:
- pubs:24907
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
The type III needle and the damage done.
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