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Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

Abstract:
Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with routine MTBC diagnostic workflows.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/S2213-2600(15)00466-X

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Institution:
University of Oxford
Department:
Oxford, MSD, Nuffield Department of Population Health, Population Health
Role:
Author
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Oxford NIHR Biomedical Research Centre More from this funder
Department of Health More from this funder
Wellcome Trust More from this funder
British Colombia Centre for Disease Control Foundation for Population and Public Health More from this funder
Department of Clinical Microbiology, Trinity College Dublin More from this funder
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Publisher:
Elsevier: Lancet Publisher's website
Journal:
The Lancet Respiratory Medicine Journal website
Publication date:
2015-12-03
DOI:
ISSN:
2213-2600
URN:
uuid:1048dd74-0c12-4c60-99a3-bf7ac3e567d8
Source identifiers:
579578
Local pid:
pubs:579578

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