Journal article
Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial
- Abstract:
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Background
Single low doses of primaquine, when added to artemisinin-based combination therapy, might prevent transmission of Plasmodium falciparum malaria to mosquitoes. We aimed to establish the activity and safety of four low doses of primaquine combined with dihydroartemisinin–piperaquine in male patients in Mali.Methods
In this phase 2, single-blind, dose-ranging, adaptive randomised trial, we enrolled boys and men with uncomplicated ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 762.5KB, Terms of use)
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- Publisher copy:
- 10.1016/S1473-3099(15)00479-X
Authors
- Publisher:
- Elsevier
- Journal:
- Lancet Infectious Diseases More from this journal
- Volume:
- 16
- Issue:
- 6
- Pages:
- 674–684
- Publication date:
- 2016-02-20
- DOI:
- EISSN:
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1474-4457
- ISSN:
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1473-3099
- Language:
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English
- Pubs id:
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pubs:607275
- UUID:
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uuid:102d67c1-0b3a-4227-a130-7dcd4168841e
- Local pid:
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pubs:607275
- Source identifiers:
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607275
- Deposit date:
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2016-06-08
- ARK identifier:
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2016
- Rights statement:
- © 2016 Elsevier Ltd. All rights reserved.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/S1473-3099(15)00479-X
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