Journal article
Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel.
- Abstract:
-
The epithelial sodium channel (ENaC) and the secretory potassium channel (Kir1.1/ROMK) are expressed in the apical membrane of renal collecting duct principal cells where they provide the rate-limiting steps for Na(+) absorption and K(+) secretion. The cystic fibrosis transmembrane conductance regulator (CFTR) is thought to regulate the function of both ENaC and Kir1.1. We hypothesized that CFTR may provide a regulatory link between ENaC and Kir1.1. In Xenopus laevis oocytes co-expressing bot...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 277
- Issue:
- 28
- Pages:
- 25377-25384
- Publication date:
- 2002-07-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
6360
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:6360
- UUID:
-
uuid:1002baaa-d22b-477d-8396-b7b9045e31d7
- Local pid:
- pubs:6360
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2002
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