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[Current knowledge on the genetic factors involved in moyamoya disease].

Abstract:

Moyamoya disease (MMD) is characterized by progressive stenosis and occlusion of the terminal portion of the bilateral carotid arteries as well as arterial collateral vessels. The etiology of MMD, however, remains unknown. Several pieces of evidence suggest the involvement of genetic factors in MMD: over 10% of MMD patients have affected blood relatives; concordance in the affection status has been proven in 80% of identical twins; and there is an ethnic predisposition to MMD, the incidence o...

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Authors


Hashikata, H More by this author
Mineharu, Y More by this author
Takenaka, K More by this author
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Journal:
Brain and nerve = Shinkei kenkyu no shinpo
Volume:
60
Issue:
11
Pages:
1261-1269
Publication date:
2008-11-05
EISSN:
1344-8129
ISSN:
1881-6096
URN:
uuid:10002c0d-285f-4202-bb30-4131f7dfe124
Source identifiers:
311496
Local pid:
pubs:311496

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