Journal article icon

Journal article

Reduced brain functional reserve and altered functional connectivity in patients with multiple sclerosis.

Abstract:

Cognitive dysfunction (affecting particularly attention and working memory) occurs early in patients with multiple sclerosis. Previous studies have focused on identifying potentially adaptive functional reorganization through recruitment of new brain regions that could limit expression of these deficits. However, lesion studies remind us that functional specializations in the brain make certain brain regions necessary for a given task. We therefore have asked whether altered functional intera...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/brain/awh670

Authors


Cifelli, A More by this author
Abu-Omar, Y More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Matthews, PM More by this author
Journal:
Brain : a journal of neurology
Volume:
129
Issue:
Pt 2
Pages:
527-537
Publication date:
2006-02-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:0fde9c80-1777-4b5f-948d-15842c69244e
Source identifiers:
241681
Local pid:
pubs:241681

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP