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Atorvastatin Impairs Pathways Associated With Skeletal Muscle Function and Health in Myoblasts From Older Adults

Abstract:

Background: Statins are widely prescribed to reduce low‐density lipoprotein (LDL) cholesterol to decrease the risk of cardiovascular disease. However, there are ongoing concerns surrounding the frequently reported skeletal muscle side effects. These include muscle pain, weakness and reduced function and are defined as statin‐associated muscle symptoms (SAMS). This study aimed to characterise the biological processes, which underlie SAMS through analysing in vitro muscle cell phenotypic and tr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/rco2.70034

Authors

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Role:
Author
ORCID:
0009-0000-9581-4805


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Funder identifier:
https://ror.org/04e3zg361
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Funder identifier:
https://ror.org/02ymzm013
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Funder identifier:
https://ror.org/04hwsx993
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Funder identifier:
https://ror.org/01ryk1543
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Funder identifier:
https://ror.org/0187kwz08


Publisher:
Wiley
Journal:
JCSM Communications More from this journal
Volume:
9
Issue:
1
Article number:
e70034
Publication date:
2026-03-03
Acceptance date:
2025-12-26
DOI:
EISSN:
2996-1394
ISSN:
2996-1394


Language:
English
Keywords:
Pubs id:
2390771
Local pid:
pubs:2390771
Source identifiers:
3816917
Deposit date:
2026-03-03
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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