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A proteomic view of the Plasmodium falciparum life cycle.

Abstract:

The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which to conduct comparative proteomics studies of this human pathogen. Here, we applied a high-throughput proteomics approach to identify new potential drug and vaccine targets and to better understand the biology of this complex protozoan parasite. We characterized four stages of the parasite life cycle (sporozoites, merozoites, trophozoites and gametocytes) by multidimensional protein identification technology...

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Publisher copy:
10.1038/nature01107

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Journal:
Nature
Volume:
419
Issue:
6906
Pages:
520-526
Publication date:
2002-10-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Source identifiers:
267313
Language:
English
Keywords:
Pubs id:
pubs:267313
UUID:
uuid:0fac694a-d8fa-4b5b-a5b8-fdfbce78a6c4
Local pid:
pubs:267313
Deposit date:
2012-12-19

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