Molecular genetic dissection of the sex-specific and vital functions of the Drosophila melanogaster sex determination gene fruitless.

Journal article

A multibranched hierarchy of regulatory genes controls all aspects of somatic sexual development in Drosophila melanogaster. One branch of this hierarchy is headed by the fruitless (fru) gene and functions in the central nervous system, where it is necessary for male courtship behavior as well as the differentiation of a male-specific abdominal structure, the muscle of Lawrence (MOL). A preliminary investigation of several of the mutations described here showed that the fru gene also has a se...

Expand abstract

Authors: Anand, A; Villella, A; Ryner, L; Carlo, T; Goodwin, S

• Publication status: Published
• Journal: Genetics
• Volume: 158
• Issue: 4
• Pages: 1569-1595
• Publication date: 2001-08-01
• EISSN: 1943-2631
• ISSN: 0016-6731
• Language: English
• Keywords: RNA, Messenger; Male; Neurons; Nerve Tissue Proteins; Transcription Factors; Alleles; Cell Differentiation; Models, Biological; Mutation; Drosophila melanogaster; Genotype; Sex Determination Processes; Phenotype; Fertility; Drosophila Proteins; Animals; Models, Genetic; Female; Sexual Behavior, Animal; Sex Factors; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic