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Journal article

Definition of the range and distribution of human immunodeficiency virus macrophage tropism using PCR-based infectivity measurements.

Abstract:

The tropism of human immunodeficiency virus (HIV) for macrophages (m phi) is a well recognized phenomenon, but the range and distribution of m phi-tropic phenotypes have not been defined by quantitative means. This study uses a PCR-based infectivity assay to derive an index of m phi tropism for several common strains of HIV. The results show that m phi tropism varies over about six orders of magnitude and that the most m phi-tropic strains have a higher infectivity for m phi than for peripher...

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Publication status:
Published

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Publisher copy:
10.1099/0022-1317-75-7-1597

Authors


Journal:
The Journal of general virology
Volume:
75 ( Pt 7)
Issue:
7
Pages:
1597-1603
Publication date:
1994-07-05
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
URN:
uuid:0f8c1fed-bec0-45ba-865c-3435f0e0537c
Source identifiers:
16354
Local pid:
pubs:16354

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