Journal article
Structure and mechanism of the oestrogen receptor
- Abstract:
- We have determined the structures of the oestrogen receptor ligand-binding domain in complex with a range of ligands and with fragments of co-regulator proteins. These structures provide insights into the structural mechanisms underlying the receptor's complex pharmacological properties and how the conformation of the receptor modulates its ability to recruit co-regulators that are necessary for transcriptional activation.
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Authors
- Journal:
- Biochemical Society Transactions More from this journal
- Volume:
- 31
- Issue:
- 1
- Pages:
- 56-59
- Publication date:
- 2003-02-01
- ISSN:
-
0300-5127
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:317569
- UUID:
-
uuid:0f833750-2354-4764-9d0d-f7ab3405f2fc
- Local pid:
-
pubs:317569
- Source identifiers:
-
317569
- Deposit date:
-
2012-12-19
- ARK identifier:
Terms of use
- Copyright date:
- 2003
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