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Journal article

'Toxgnostics': an unmet need in cancer medicine.

Abstract:

If we were to summarize the rationale that underpins medical oncology in a Latin aphorism, it might be 'veneno ergo sum'; that is, I poison, therefore I am. The burden of chemotherapy-associated toxicity is well recognized, but we have relatively few tools that increase the precision of anticancer drug prescribing. We propose a shift in emphasis from the focussed study of polymorphisms in drug metabolic pathways in small sets of patients to broader agnostic analyses to systematically correlat...

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Publication status:
Published

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Publisher copy:
10.1038/nrc3729

Authors


Domingo, E More by this author
Rosmarin, D More by this author
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Journal:
Nature reviews. Cancer
Volume:
14
Issue:
6
Pages:
440-445
Publication date:
2014-06-05
DOI:
EISSN:
1474-1768
ISSN:
1474-175X
URN:
uuid:0f63395f-f633-42bc-8a54-6541c3e34e5f
Source identifiers:
465135
Local pid:
pubs:465135

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