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Validity of indirect comparison for estimating efficacy of competing interventions: empirical evidence from published meta-analyses.

Abstract:

OBJECTIVE: To determine the validity of adjusted indirect comparisons by using data from published meta-analyses of randomised trials. DESIGN: Direct comparison of different interventions in randomised trials and adjusted indirect comparison in which two interventions were compared through their relative effect versus a common comparator. The discrepancy between the direct and adjusted indirect comparison was measured by the difference between the two estimates. DATA SOURCES: Database of abs...

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Publication status:
Published

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Publisher copy:
10.1136/bmj.326.7387.472

Authors


Altman, DG More by this author
Glenny, AM More by this author
Journal:
BMJ (Clinical research ed.)
Volume:
326
Issue:
7387
Pages:
472
Publication date:
2003-03-05
DOI:
EISSN:
1756-1833
ISSN:
0959-8138
URN:
uuid:0f5d2d20-a172-42fc-bf84-3b003f94c43d
Source identifiers:
317951
Local pid:
pubs:317951

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