See-saw rocking: an in vitro model for mechanotransduction research.

Journal article

In vitro mechanotransduction studies, uncovering the basic science of the response of cells to mechanical forces, are essential for progress in tissue engineering and its clinical application. Many varying investigations have described a multitude of cell responses; however, as the precise nature and magnitude of the stresses applied are infrequently reported and rarely validated, the experiments are often not comparable, limiting research progress. This paper provides physical and biological...

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Authors: Tucker, R; Henningsson, P; Franklin, S; Chen, D; Ventikos, Y

• Publication status: Published
• Publisher: Royal Society of London
• Journal: Journal of the Royal Society, Interface / the Royal Society
• Volume: 11
• Issue: 97
• Pages: 20140330
• Publication date: 2014-08-01
• DOI: 10.1098/rsif.2014.0330
• EISSN: 1742-5662
• ISSN: 1742-5689
• Language: English
• Keywords: Cells, Cultured; Flow Cytometry; Equipment Failure Analysis; Computer Simulation; Humans; Stress, Mechanical; Models, Biological; Tendons; Equipment Design; Mechanotransduction, Cellular; Physical Stimulation; Oscillometry; Microfluidic Analytical Techniques; Micromanipulation