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Journal article

Alternative activation of macrophages: an immunologic functional perspective.

Abstract:

Macrophages are innate immune cells with well-established roles in the primary response to pathogens, but also in tissue homeostasis, coordination of the adaptive immune response, inflammation, resolution, and repair. These cells recognize danger signals through receptors capable of inducing specialized activation programs. The classically known macrophage activation is induced by IFN-gamma, which triggers a harsh proinflammatory response that is required to kill intracellular pathogens. Macr...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Annual review of immunology
Volume:
27
Issue:
1
Pages:
451-483
Publication date:
2009-01-01
DOI:
EISSN:
1545-3278
ISSN:
0732-0582
URN:
uuid:0f49388c-1c5d-4c9c-af6b-430b000d1103
Source identifiers:
18814
Local pid:
pubs:18814

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