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Linzagolix, with and without add-back therapy, in women with endometriosis-associated pain: results from EDELWEISS 6, a double-blind randomized extension and withdrawal study

Abstract:

STUDY QUESTION: Was the efficacy of linzagolix, observed at 6 months in women with endometriosis-associated pain, maintained when administered for an additional 6 months? SUMMARY ANSWER: Efficacy from this extension study complements the results of the main trial, by showing that linzagolix is effective at reducing endometriosis-associated pain for a majority of women. WHAT IS KNOWN ALREADY: In the pivotal EDELWEISS 3 randomized controlled trial, the efficacy and safety of 24 weeks of once-da...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/hropen/hoag030

Authors

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Role:
Author
ORCID:
0000-0003-2528-206X
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-9870-9581
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Role:
Author
ORCID:
0000-0002-8851-625X
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Role:
Author
ORCID:
0000-0002-9656-493X


Publisher:
Oxford University Press
Journal:
Human Reproduction Open More from this journal
Volume:
2026
Issue:
2
Pages:
hoag030
Article number:
hoag030
Publication date:
2026-04-08
Acceptance date:
2026-04-02
DOI:
EISSN:
2399-3529
ISSN:
2399-3529


Language:
English
Keywords:
Source identifiers:
4008921
Deposit date:
2026-05-02
ARK identifier:
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