Journal article

Induction of labour versus standard care to prevent shoulder dystocia in fetuses suspected to be large for gestational age in the UK (the Big Baby trial): a multicentre, open-label, randomised controlled trial

Abstract:: Background: The benefits and harms of early induction of labour to reduce shoulder dystocia in fetuses suspected to be large for gestational age (LGA) are uncertain. We aimed to investigate whether early induction of labour is associated with a reduced risk of shoulder dystocia compared with standard care.

Methods: In this open-label, randomised controlled phase 3 trial, women aged ≥18 years with a suspected LGA fetus (estimated fetal weight >90...
Expand abstract
Collapse abstract

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Gardosi, J., Ewington, L. J., Booth, K., Bick, D., Bouliotis, G., Butler, E., Deshpande, S., Ellson, H., Fisher, J., Gornall, A., Lall, R., Mistry, H., Naghdi, S., Petrou, S., Slowther, A.-M., Wood, S., Underwood, M., & Quenby, S. (2025). Induction of labour versus standard care to prevent shoulder dystocia in fetuses suspected to be large for gestational age in the UK (the Big Baby trial): a multicentre, open-label, randomised controlled trial. Lancet, 405(10491), 1743–1756.

MLA Style

Gardosi, J, et al. “Induction of Labour versus Standard Care to Prevent Shoulder Dystocia in Fetuses Suspected to Be Large for Gestational Age in the UK (the Big Baby Trial): a Multicentre, Open-Label, Randomised Controlled Trial.” Lancet, vol. 405, no. 10491, 2025, pp. 1743–56.

Chicago Style

Gardosi, J, LJ Ewington, K Booth, et al. 2025. “Induction of Labour versus Standard Care to Prevent Shoulder Dystocia in Fetuses Suspected to Be Large for Gestational Age in the UK (the Big Baby Trial): a Multicentre, Open-Label, Randomised Controlled Trial.” Lancet 405 (10491): 1743–56.
Print

Access Document

Files:: Gardosi_et_al_2025_Induction_of_labour.pdf

(Preview, Version of record, pdf, 315.1KB, Terms of use)

Publisher copy:: 10.1016/s0140-6736(25)00162-x

Authors

+ Gardosi, J More by this author

Role:: Author

+ Ewington, LJ More by this author

Role:: Author

+ Booth, K More by this author

Role:: Author

+ Bick, D More by this author

Role:: Author

+ Bouliotis, G More by this author

Role:: Author

More authors...

+ National Institute for Health and Care Research More from this funder

Funder identifier:: https://ror.org/0187kwz08
Grant:: NIHR202402

Publisher:: Elsevier
Journal:: Lancet More from this journal
Volume:: 405
Issue:: 10491
Pages:: 1743-1756
Publication date:: 2025-05-01
Acceptance date:: 2025-01-23
DOI:: 10.1016/s0140-6736(25)00162-x
EISSN:: 1474-547X
ISSN:: 0140-6736

Language:: English
Pubs id:: 2121384
Local pid:: pubs:2121384
Deposit date:: 2025-05-02
ARK identifier:: ark:/29072/ora_0f1f2f7cd4d64885b7232b0f5074bdb4

Terms of use

Copyright holder:: Gardosi et al.
Copyright date:: 2025
Rights statement:: © 2025 The Authors. Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC 4.0 license.

Licence:: CC Attribution-NonCommercial (CC BY-NC)

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP