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Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke.

Abstract:

Early after acute ischaemic stroke, elevation of brain temperature might augment tissue metabolic rate and conversion of ischaemic but viable tissue to infarction. This might explain the observed link between pyrexia, severe stroke and poor outcome. We tested this hypothesis by measuring brain temperature and lactate concentration with multi-voxel magnetic resonance spectroscopic imaging across the acute ischaemic stroke lesion and normal brain as determined on diffusion imaging. We compared ...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awp010

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Journal:
Brain : a journal of neurology
Volume:
132
Issue:
Pt 4
Pages:
955-964
Publication date:
2009-04-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:0f05e7e3-f2fb-4556-8eb4-c644f5e1d5da
Source identifiers:
227274
Local pid:
pubs:227274

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