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Widening the usefulness of epoxides and aziridines in synthesis

Abstract:
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithium amides allows the regio- and stereoselective formation of α-lithiated species. Judicious choice of reaction conditions allows these species to operate as nucleophiles, enolate equivalents, vinyl cation equivalents, or carbenes. © 2007 IUPAC.

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Publisher copy:
10.1351/pac200779020269

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Pure and Applied Chemistry More from this journal
Volume:
79
Issue:
2
Pages:
269-279
Publication date:
2007-02-01
DOI:
ISSN:
0033-4545


Language:
English
Keywords:
Pubs id:
pubs:102245
UUID:
uuid:0ef433b2-3b53-497b-8e8b-4d84af3dd111
Local pid:
pubs:102245
Source identifiers:
102245
Deposit date:
2012-12-19
ARK identifier:

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