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Tuberculous meningitis in adults: a review of a decade of developments focusing on prognostic factors for outcome.

Abstract:

Tuberculous meningitis (TBM) is the most severe form of TB. Despite treatment, mortality and long-term disability remain unacceptably high. Prevention, early recognition, diagnosis and treatment are fundamental to improving outcomes. However, an effective vaccine remains elusive, initial symptoms are nonspecific, and sensitive diagnostic tests are not available. There has been progress in our understanding of the immunopathology of TBM, and several factors have been found to be associated wit...

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Publication status:
Published

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Publisher copy:
10.2217/fmb.12.86

Authors


Brancusi, F More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Heemskerk, D More by this author
Journal:
Future microbiology
Volume:
7
Issue:
9
Pages:
1101-1116
Publication date:
2012-09-05
DOI:
EISSN:
1746-0921
ISSN:
1746-0913
URN:
uuid:0eef2ea4-ab4d-474d-a8f9-1161a042b3dd
Source identifiers:
352742
Local pid:
pubs:352742

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