A non-invasive method of measuring concentrations of rubidium in rat skeletal muscle in vivo by 87Rb nuclear magnetic resonance spectroscopy: implications for the measurement of cation transport activity in vivo.

Journal article

1. We have used n.m.r. spectroscopy to measure rubidium concentrations in the skeletal muscle of live intact rats. Using a 1.9 T superconducting magnet and an ear-phone coil tuned to both protons (1H) and rubidium (87Rb), it was possible to make measurements of both tissue rubidium content and water content, and from these measurements to obtain the rubidium concentration. 2. The n.m.r. estimate of rubidium concentration in muscle in vivo was found to be a constant 31% (SEM 4%) of that estima...

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Authors: Syme, P; Dixon, R; Allis, J; Aronson, J; Grahame-Smith, D

• Publication status: Published
• Journal: Clinical science (London, England : 1979)
• Volume: 78
• Issue: 3
• Pages: 303-309
• Publication date: 1990-03-01
• EISSN: 1470-8736
• ISSN: 0143-5221
• Language: English
• Keywords: Animals; Magnetic Resonance Spectroscopy; Rats; Electric Conductivity; Spectrophotometry, Atomic; Sodium-Potassium-Exchanging ATPase; Water; Biological Transport, Active; Male; Rubidium; Rats, Inbred WKY; Muscles