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Journal article

Coordinated control of XerC and XerD catalytic activities during Holliday junction resolution.

Abstract:

Site-specific recombinases XerC and XerD function in the segregation of circular bacterial replicons. In a recombining nucleoprotein complex containing two molecules each of XerC and XerD, coordinated reciprocal switches in recombinase activity ensure that only XerC or XerD is active at any one time. Mutated recombinases that carry sub?stitutions of a catalytic arginine residue stimulate cleavage and strand exchange mediated by the partner recombinase on DNA substrates that are normally recom...

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Publication status:
Published

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Publisher copy:
10.1006/jmbi.2000.3762

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
Journal of molecular biology
Volume:
299
Issue:
2
Pages:
391-403
Publication date:
2000-06-05
DOI:
EISSN:
1089-8638
ISSN:
0022-2836
URN:
uuid:0ed6ee1e-4eca-4c4e-a159-e35fe022bce1
Source identifiers:
100048
Local pid:
pubs:100048

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