Journal article icon

Journal article

A malaria membrane skeletal protein is essential for normal morphogenesis, motility, and infectivity of sporozoites.

Abstract:

Membrane skeletons are structural elements that provide mechanical support to the plasma membrane and define cell shape. Here, we identify and characterize a putative protein component of the membrane skeleton of the malaria parasite. The protein, named PbIMC1a, is the structural orthologue of the Toxoplasma gondii inner membrane complex protein 1 (TgIMC1), a component of the membrane skeleton in tachyzoites. Using targeted gene disruption in the rodent malaria species Plasmodium berghei, we ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1083/jcb.200406068

Authors


Khater, EI More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Dessens, JT More by this author
Journal:
The Journal of cell biology
Volume:
167
Issue:
3
Pages:
425-432
Publication date:
2004-11-05
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
URN:
uuid:0ed10328-9b5e-44a5-9b56-a0d2d002871b
Source identifiers:
258391
Local pid:
pubs:258391

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP