Journal article icon

Journal article

Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase.

Abstract:

OBJECTIVE: To map the antibody response to human citrullinated alpha-enolase, a candidate autoantigen in rheumatoid arthritis (RA), and to examine cross-reactivity with bacterial enolase. METHODS: Serum samples obtained from patients with RA, disease control subjects, and healthy control subjects were tested by enzyme-linked immunosorbent assay (ELISA) for reactivity with citrullinated alpha-enolase peptides. Antibodies specific for the immunodominant epitope were raised in rabbits or were p...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/art.23936

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Arthritis and rheumatism
Volume:
58
Issue:
10
Pages:
3009-3019
Publication date:
2008-10-01
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
Source identifiers:
230540

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP