Single dose oral ibuprofen plus codeine for acute postoperative pain in adults.

Journal article

BACKGROUND: There is good evidence that combining two different analgesics in fixed doses in a single tablet can provide better pain relief in acute pain and headache than either drug alone, and that the drug-specific effects are essentially additive. This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations and when tested in the same and different trials. Some combinations of ibuprofen and codeine are available without prescrip...

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Authors: Derry, S; Karlin, S; Moore, R

• Publication status: Published
• Journal: Cochrane database of systematic reviews
• Volume: 3
• Issue: 3
• Pages: CD010107
• Publication date: 2013-01-01
• DOI: 10.1002/14651858.cd010107.pub2
• EISSN: 1469-493X
• ISSN: 1469-493X
• Language: English
• Keywords: Codeine; Analgesics, Opioid; Drug Combinations; Adult; Pain, Postoperative; Treatment Outcome; Randomized Controlled Trials as Topic; Humans; Ibuprofen