Journal article icon

Journal article

Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data.

Abstract:

BACKGROUND: The efficacy of RTS,S/AS01 as a vaccine for malaria is being tested in a phase 3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria and severe malaria. To ascertain variations in vaccine efficacy according to covariates such as transmission intensity, choice of adjuvant, age at vaccination, and bednet use, we did an individual-participant pooled analysis of phase 2 clinical data. METHODS: We analysed data from 11 different sites in ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Lusingu, JP More by this author
Expand authors...
Journal:
The Lancet. Infectious diseases
Volume:
13
Issue:
4
Pages:
319-327
Publication date:
2013-04-05
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
URN:
uuid:0ebf6ce2-8cf4-451c-bba0-0808751ccfd4
Source identifiers:
387853
Local pid:
pubs:387853

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP