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Journal article

Genetic epidemiology: the use of old and new tools for multiple sclerosis.

Abstract:

We review the practical application of the tools for studying the genetic epidemiology of complex disease. Whole-genome association studies highlight the need to understand the genetic epidemiology. Elucidating the genetic basis of disease anticipated from these studies has been incomplete, and the importance of the environment and its potential interaction with genes cannot be overlooked. Multiple sclerosis yields several key lessons including how epistatic effects might overshadow the small...

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Publication status:
Published

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Publisher copy:
10.1016/j.tins.2008.09.001

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Dyment, DA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Journal:
Trends in neurosciences
Volume:
31
Issue:
12
Pages:
645-652
Publication date:
2008-12-05
DOI:
EISSN:
1878-108X
ISSN:
0166-2236
URN:
uuid:0e828d87-24ed-4f3a-b371-1dc9e8964a73
Source identifiers:
34440
Local pid:
pubs:34440

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