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Journal article

An investigation into the prognostic significance of necrosis and hypoxia in high grade and invasive bladder cancer.

Abstract:

PURPOSE: We investigated hypoxia and necrosis in high grade and invasive bladder cancer, and related this to prognosis. MATERIALS AND METHODS: We performed a retrospective observational study of 98 primary cystectomy specimens scored for necrosis, and the hypoxia associated markers carbonic anhydrase IX, hypoxia-inducible factor 1 alpha and 2 alpha, and Bcl2/adenovirus EIB 19 kDa interacting protein 3. Tumor tissue array was used with cores taken from representative and perinecrotic tumor re...

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Publication status:
Published

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Publisher copy:
10.1016/j.juro.2007.03.112

Authors


Agrawal, S More by this author
Thamboo, TP More by this author
Roberts, I More by this author
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Journal:
The Journal of urology
Volume:
178
Issue:
2
Pages:
677-682
Publication date:
2007-08-05
DOI:
EISSN:
1527-3792
ISSN:
0022-5347
URN:
uuid:0e5f0bde-260d-4348-a01c-4192112cdacb
Source identifiers:
244836
Local pid:
pubs:244836

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