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Determination of Optimal Diagnostic Cut-Offs for the Naval Medical Research Centre Scrub Typhus IgM ELISA in Chiang Rai, Thailand.

Abstract:

In this diagnostic accuracy study, we evaluated data from 135 febrile patients from Chiang Rai, to determine the optimal optical density (OD) cutoffs for an in-house scrub typhus IgM ELISA. Receiver operating characteristic curves were generated using a panel of reference assays, including an IgM immunofluorescence assay (IFA), PCR, in vitro isolation, presence of an eschar, or a combination of these. Altogether, 33 patients (24.4%) were diagnosed as having scrub typhus. Correlation between p...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.4269/ajtmh.18-0675

Authors


Phanichkrivalkosil, M More by this author
Tanganuchitcharnchai, A More by this author
Jintaworn, S More by this author
Kantipong, P More by this author
Laongnualpanich, A More by this author
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Publisher:
The American Society of Troppical Medicine and Hygeine Publisher's website
Journal:
The American Journal of Tropical Medicine and Hygeine Journal website
Volume:
100
Issue:
5
Pages:
1134-1140
Publication date:
2019-05-01
Acceptance date:
2019-01-27
DOI:
ISSN:
1476-1645 and 0002-9637
Pubs id:
pubs:983980
URN:
uri:0e5564cd-36b2-4b5a-8081-498617d54a80
UUID:
uuid:0e5564cd-36b2-4b5a-8081-498617d54a80
Local pid:
pubs:983980
Language:
English
Keywords:

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