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Journal article

PTPsigma promotes retinal neurite outgrowth non-cell-autonomously.

Abstract:

The receptor-like protein tyrosine phosphatase (RPTP) PTPsigma controls the growth and targeting of retinal axons, both in culture and in ovo. Although the principal actions of PTPsigma have been thought to be cell-autonomous, the possibility that RPTPs related to PTPsigma also have non-cell-autonomous signaling functions during axon development has also been supported genetically. Here we report that a cell culture substrate made from purified PTPsigma ectodomains supports retinal neurite ou...

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Publication status:
Published

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Publisher copy:
10.1002/neu.20175

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Role:
Author
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Journal:
Journal of neurobiology
Volume:
65
Issue:
1
Pages:
59-71
Publication date:
2005-10-05
DOI:
EISSN:
1097-4695
ISSN:
0022-3034
URN:
uuid:0e3f41c6-f8e8-4f81-8737-ff981696a923
Source identifiers:
14060
Local pid:
pubs:14060

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