Placental size at 19 weeks predicts offspring bone mass at birth: findings from the Southampton Women's Survey.

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OBJECTIVES: In this study we investigate the relationships between placental size and neonatal bone mass and body composition, in a population-based cohort. STUDY DESIGN: 914 mother-neonate pairs were included. Placental dimensions were measured via ultrasound at 19 weeks gestation. Dual X-ray absorptiometry (DXA) was performed on the neonates within the first two weeks of life. RESULTS: We observed positive relationships between placental volume at 19 weeks, and neonatal bone area (BA; r = 0...

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Authors: Holroyd, C; Harvey, N; Crozier, SR; Winder, N; Mahon, P

• Publication status: Published
• Host title: Placenta
• Volume: 33
• Issue: 8
• Pages: 623-629
• Publication date: 2012-08-01
• Event location: England
• DOI: 10.1016/j.placenta.2012.04.007
• EISSN: 1532-3102
• ISSN: 0143-4004
• Keywords: Calcification, Physiologic; Male; Placentation; Infant, Newborn; Adult; Osteogenesis; Organ Size; Bone Density; England; Longitudinal Studies; Pregnancy; Ultrasonography, Prenatal; Cohort Studies; Placental Insufficiency; Fetal Growth Retardation; Health Surveys; Prospective Studies; SWS Study Group; Female; Humans; Placenta; Pregnancy Trimester, Second