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Swimming with protists: perception, motility and flagellum assembly.

Abstract:
In unicellular and multicellular eukaryotes, fast cell motility and rapid movement of material over cell surfaces are often mediated by ciliary or flagellar beating. The conserved defining structure in most motile cilia and flagella is the '9+2' microtubule axoneme. Our general understanding of flagellum assembly and the regulation of flagellar motility has been led by results from seminal studies of flagellate protozoa and algae. Here we review recent work relating to various aspects of protist physiology and cell biology. In particular, we discuss energy metabolism in eukaryotic flagella, modifications to the canonical assembly pathway and flagellum function in parasite virulence.
Publication status:
Published

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Publisher copy:
10.1038/nrmicro2009

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author


Journal:
Nature reviews. Microbiology More from this journal
Volume:
6
Issue:
11
Pages:
838-850
Publication date:
2008-11-01
DOI:
EISSN:
1740-1534
ISSN:
1740-1526


Language:
English
Keywords:
Pubs id:
pubs:57894
UUID:
uuid:0e08f5d7-6228-4814-ab60-b7c1f2b3cc15
Local pid:
pubs:57894
Source identifiers:
57894
Deposit date:
2012-12-19
ARK identifier:

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