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Journal article

Some p53-binding proteins that can function as arbiters of life and death.

Abstract:

Four sets of p53-binding proteins are discussed in this review. These are the E2F family, the ASPP family, Y-box-binding protein YB1, and the prolyl isomerase Pin1. Each appears to play a role in the decision by p53 to induce an arrest of cell proliferation or apoptosis and they may also be independent markers of cancer. Their activities appear to be linked with the cell cycle and they may also interact with each other. In this review, the properties of each protein class are discussed as wel...

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Publication status:
Published

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Publisher copy:
10.1038/sj.cdd.4401924

Authors


Braithwaite, AW More by this author
Del Sal, G More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Ludwig Institute
Journal:
Cell death and differentiation
Volume:
13
Issue:
6
Pages:
984-993
Publication date:
2006-06-05
DOI:
EISSN:
1476-5403
ISSN:
1350-9047
URN:
uuid:0e029249-1c16-4306-9216-314cc60cc048
Source identifiers:
84051
Local pid:
pubs:84051

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