Journal article icon

Journal article

Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: results from the pancreatic cancer cohort consortium.

Abstract:

BACKGROUND: Subjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A(1) versus A(2) variant, whereas O01 and O02 variants are nonfunctioning. We hypothesized: 1) A(1) allele would confer greater risk than A(2) allele, 2) protective effect of the O allele would be equivalent for O01 and O02 variants, 3) secretor phenotype would modify the association with risk. METHODS: We determined ABO variants and secretor phenot...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Wolpin, BM More by this author
Steplowski, E More by this author
Olsson, ML More by this author
Expand authors...
Journal:
Cancer epidemiology, biomarkers and prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Volume:
19
Issue:
12
Pages:
3140-3149
Publication date:
2010-12-05
DOI:
EISSN:
1538-7755
ISSN:
1055-9965
URN:
uuid:0df04230-a86b-45be-96de-6e93e83b7062
Source identifiers:
110374
Local pid:
pubs:110374

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP