Journal article
Palladium-catalyzed allylic fluorination.
- Abstract:
- Mild and rapid: The title reaction is presented and its applicability to 18F radiolabeling is demonstrated (see scheme; TBAF=tetra-n- butylammonium fluoride, THF=tetrahydrofuran, dba=dibenzylideneacetone). The use of p-nitrobenzoate as the leaving group is significant to the success of this catalytic organometallic fluorination process. A range of allylic fluorides were synthesized by this method. Copyright © 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
- Publication status:
- Published
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- Publisher copy:
- 10.1002/anie.201007307
Authors
- Journal:
- Angewandte Chemie (International ed. in English) More from this journal
- Volume:
- 50
- Issue:
- 11
- Pages:
- 2613-2617
- Publication date:
- 2011-03-01
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:120221
- UUID:
-
uuid:0deaca31-b997-4ff5-94da-eb8dfc5f9665
- Local pid:
-
pubs:120221
- Source identifiers:
-
120221
- Deposit date:
-
2012-12-19
- ARK identifier:
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- Copyright date:
- 2011
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