Journal article
The role of the HNF4alpha enhancer in type 2 diabetes.
- Abstract:
-
The genetic causes of type 2 diabetes are not well understood. The disease has been linked to chromosome 20q12-q13.1 a region which harbors the transcription factor HNF4alpha. Mutations in the coding region of HNF4alpha cause maturity onset diabetes of the young, an autosomal dominant form of diabetes, but do not account for the linkage to this region. An enhancer element has recently been characterized 6 kb 5' of the HNF4alpha P1 promoter containing binding sites for the transcription factor...
Expand abstract
Actions
Authors
Bibliographic Details
- Journal:
- Molecular genetics and metabolism
- Volume:
- 76
- Issue:
- 2
- Pages:
- 148-151
- Publication date:
- 2002-06-01
- DOI:
- EISSN:
-
1096-7206
- ISSN:
-
1096-7192
- Source identifiers:
-
6668
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:6668
- UUID:
-
uuid:0de29c3c-16b2-4c43-86b0-d91441a5d668
- Local pid:
- pubs:6668
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2002
If you are the owner of this record, you can report an update to it here: Report update to this record