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Efficacy and safety of statin therapy in older people: meta-analysis of individual participant data from 28 randomised controlled trials

Abstract:

Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin thera...

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Publication status:
Published
Peer review status:
Peer revivewed
Version:
Publisher's version

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Publisher copy:
10.1016/S0140-6736(18)31942-1

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Population Health
Oxford college:
St Cross College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Population Health
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
393
Issue:
10170
Pages:
407-415
Publication date:
2019-02-02
Acceptance date:
2018-08-14
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pubs id:
pubs:921953
URN:
uri:0db1241b-e731-4aaf-9f3e-ab3596ebb670
UUID:
uuid:0db1241b-e731-4aaf-9f3e-ab3596ebb670
Local pid:
pubs:921953

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