Journal article
Efficacy and safety of statin therapy in older people: meta-analysis of individual participant data from 28 randomised controlled trials
- Abstract:
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Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages.
Methods: In this meta-analysis, randomised trials of statin therapy were eligible if they aimed to recruit at least 1000 p...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 653.4KB, Terms of use)
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(Preview, Supplementary materials, pdf, 843.1KB, Terms of use)
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- Publisher copy:
- 10.1016/S0140-6736(18)31942-1
Authors
- Publisher:
- Elsevier
- Journal:
- Lancet More from this journal
- Volume:
- 393
- Issue:
- 10170
- Pages:
- 407-415
- Publication date:
- 2019-01-31
- Acceptance date:
- 2018-08-14
- DOI:
- EISSN:
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1474-547X
- ISSN:
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0140-6736
- Language:
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English
- Keywords:
- Pubs id:
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pubs:921953
- UUID:
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uuid:0db1241b-e731-4aaf-9f3e-ab3596ebb670
- Local pid:
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pubs:921953
- Source identifiers:
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921953
- Deposit date:
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2018-09-26
Terms of use
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2018
- Rights statement:
- Crown Copyright © 2018 Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
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