Journal article
The ferret auditory cortex: descending projections to the inferior colliculus
- Abstract:
- Descending corticofugal projections are thought to play a critical role in shaping the responses of subcortical neurons. Here, we examine the origins and targets of ferret auditory corticocollicular projections. We show that the ectosylvian gyrus (EG), where the auditory cortex is located, can be subdivided into middle, anterior, and posterior regions according to the pattern of cytochrome oxidase staining and immunoreactivity for the neurofilament antibody SMI32. Injection of retrograde tracers in the inferior colliculus (IC) labeled large layer V pyramidal cells throughout the EG and adjacent sulci. Each region of the EG has a different pattern of descending projections. Neurons in the primary auditory fields in the middle EG project to the lateral nucleus (LN) of the ipsilateral IC and bilaterally to the dorsal cortex and dorsal part of the central nucleus (CN). The projection to these dorsomedial regions of the IC is predominantly ipsilateral and topographically organized. The secondary cortical fields in the posterior EG target the same midbrain areas but exclude the CN of the IC. A smaller projection to the ipsilateral LM also arises from the anterior EG, which is the only region of auditory cortex to target tegmental areas surrounding the IC, including the superior colliculus, periaqueductal gray, intercocollicular connectivity is consistent with regional differences in physiological properties and provides another basis for subdividing ferret auditory cortex into functionallly distinct areas.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.1MB, Terms of use)
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- Publisher copy:
- 10.1093/cercor/bhj164
Authors
- Publisher:
- Oxford University Press
- Journal:
- Cerebral Cortex More from this journal
- Volume:
- 17
- Issue:
- 2
- Pages:
- 475-491
- Publication date:
- 2007-02-01
- Edition:
- Publisher's version
- DOI:
- EISSN:
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1460-2199
- ISSN:
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1047-3211
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:0dadd83f-7a73-4011-b16d-a111594ddfd5
- Local pid:
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ora:1653
- Deposit date:
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2008-03-14
Terms of use
- Copyright holder:
- Victoria M Bajo et al
- Copyright date:
- 2007
- Notes:
- Originally published as: Bajor, V. M. et al. (2007). 'The ferret auditory cortex: descending projections to the inferior colliculus', Cerebral Cortex, 17(2), 475-491. [Available at http://cercor.oxfordjournals.org/]. This article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if the article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact [email protected]
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