The aim of this study was to use optical imaging with voltage-sensitive dyes (Di-4-ANEPPS), to examine the cholinergic modulation of CA1 network responses to Schaffer collateral input. By comparing responses recorded with optical imaging and field recordings across the proximodistal axis of CA1, it was initially demonstrated that voltage-sensitive dyes could report reliably both the pattern of activation and cholinergic modulation. The higher spatial resolution of optical imaging was used to ...Expand abstract
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Cholinergic modulation of the spatiotemporal pattern of hippocampal activity in vitro.
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