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Cholinergic modulation of the spatiotemporal pattern of hippocampal activity in vitro.

Abstract:

The aim of this study was to use optical imaging with voltage-sensitive dyes (Di-4-ANEPPS), to examine the cholinergic modulation of CA1 network responses to Schaffer collateral input. By comparing responses recorded with optical imaging and field recordings across the proximodistal axis of CA1, it was initially demonstrated that voltage-sensitive dyes could report reliably both the pattern of activation and cholinergic modulation. The higher spatial resolution of optical imaging was used to ...

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Publication status:
Published

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Authors


Tominaga, T More by this author
Ichikawa, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
Neuropharmacology
Volume:
48
Issue:
1
Pages:
118-133
Publication date:
2005-01-05
DOI:
EISSN:
1873-7064
ISSN:
0028-3908
URN:
uuid:0daafc8d-5eb6-4600-be2c-61ee56585b43
Source identifiers:
185146
Local pid:
pubs:185146

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