- Abstract:
-
OBJECTIVE: To establish the safety and efficacy of repeat infusions of tocilizumab (previously known as MRA), a humanized anti-interleukin-6 (IL-6) receptor antibody, alone and in combination with methotrexate (MTX), for the treatment of rheumatoid arthritis (RA). METHODS: The study group comprised 359 patients with active RA in whom the response to MTX was inadequate. During a stabilization period, these patients received their current dose of MTX for at least 4 weeks. Following stabilizati...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/art.22033
-
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- Journal:
- Arthritis and rheumatism
- Volume:
- 54
- Issue:
- 9
- Pages:
- 2817-2829
- Publication date:
- 2006-09-05
- DOI:
- EISSN:
-
1529-0131
- ISSN:
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0004-3591
- URN:
-
uuid:0da5a0b1-ae7c-4559-9773-5e80008da95a
- Source identifiers:
-
226825
- Local pid:
- pubs:226825
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.
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